The University of Rochester's Rare Books and Special Collections Department has unveiled a new website - Lincoln and his Circle - "to make available the letters to, from, and about Abraham Lincoln" in their collections. The site includes images and selected transcripts of nearly 300 letters so far, most from the William Seward Papers.
I had cause to use the Seward Papers often during my undergrad years (he's a Union alum and had a lengthy and wonderful correspondence with Eliphalet Nott, Union's longtime president). The staff at U of R were unfailingly courteous and helpful.